date:Aug 10, 2012
nted to see if grapefruit juice can be used in a controlled fashion to increase the availability and efficacy of sirolimus,he said.
The team reveal that cancer patients who drank grapefruit juice increased sirolimus levels by 350%.
This is the first cancer study to harness this drug-food interaction,the authors note.
Study details
Cohen and colleagues organised three simultaneous phase-1 clinical trials of sirolimus. Patients received only sirolimus, sirolimus plus ketoconazole (a drug known